Peptides & Performance

BPC-157, or Body Protection Compound-157, is a synthetic peptide derived from a protein found in human gastric juice. It consists of 15 amino acids and has demonstrated remarkable healing properties across various tissues. BPC-157 is particularly noted for its ability to promote angiogenesis, accelerate wound healing, and protect the gastrointestinal tract. Research has shown its efficacy in treating tendon and ligament injuries, muscle damage, and even certain gastrointestinal disorders. BPC-157 works by modulating the nitric oxide (NO) system and promoting the formation of new blood vessels, which is crucial for tissue repair and regeneration

TB-500, also known as Thymosin Beta-4, is a synthetic version of a naturally occurring 43-amino acid peptide found in virtually all human and animal cells. It plays a vital role in cell structure and function, particularly in tissue repair and regeneration. TB-500 is known for its ability to promote cell migration, reduce inflammation, and up regulate actin, a protein essential for cell structure and movement. It has shown promise in treating various injuries, including muscle tears, ligament sprains, and tendinitis. TB-500 is particularly effective in promoting the formation of new blood vessels and enhancing wound healing.

IGF-1 LR3 (Long Arginine 3-IGF-1) is a synthetic analog of human insulin-like growth factor 1 (IGF-1). It is an 83-amino acid peptide with a molecular weight of 9117.60 g/mol. IGF-1 LR3 differs from native IGF-1 by the substitution of an arginine for glutamic acid at position 3 and the addition of a 13-amino acid extension at the N-terminus. These modifications result in significantly reduced binding to IGF binding proteins, increased biological potency, and extended half-life compared to native IGF-1. Muscle Growth: Studies have demonstrated that IGF-1 LR3 can promote muscle cell proliferation and hypertrophy, making it of interest in treating muscle-wasting conditions.

CJC-1295 is a long-acting GHRH analogue that has been shown to increase growth hormone and IGF-1 levels in healthy adults. Research has indicated its potential benefits in improving body composition, enhancing fat oxidation, and promoting muscle growth. CJC-1295 has demonstrated a favorable safety profile and the ability to maintain elevated GH levels for extended periods.

Ipamorelin is a selective growth hormone secretagogue that stimulates GH release without significantly affecting other hormones. Studies have shown its potential in promoting muscle growth, improving bone density, and enhancing fat loss. Ipamorelin has also demonstrated potential benefits in sleep quality and recovery from exercise-induced muscle damage.

Sermorelin is a synthetic peptide analog of growth hormone-releasing hormone (GHRH), specifically consisting of the first 29 amino acids of the naturally occurring 44-amino acid GHRH. It is designed to stimulate the pituitary gland to produce and release endogenous growth hormone (GH). Sermorelin has been used for diagnostic evaluation of pituitary function and for treating growth hormone deficiency in children. In recent years, it has gained attention as a potential therapy for age-related growth hormone decline in adults, offering a more physiological approach to growth hormone restoration compared to direct GH administration.

SS-31 (also known as Elamipretide, MTP-131, or Bendavia) is a synthetic tetrapeptide that specifically targets mitochondria. It belongs to the Szeto-Schiller (SS) family of peptides designed to improve mitochondrial function. SS-31 has gained significant attention in research for its potential therapeutic applications in various conditions associated with mitochondrial dysfunction, including heart failure, kidney disease, neurodegenerative disorders, and aging-related diseases.

GHK-Cu (Glycyl-L-histidyl-L-lysine copper) is a naturally occurring copper peptide found in human plasma. As an injectable form, GHK-Cu has gained significant attention in regenerative medicine and anti-aging therapies. This tripeptide complex has demonstrated remarkable abilities in tissue repair, skin regeneration, and potential neuroprotective effects. GHK-Cu injectable formulations are designed to deliver these benefits systemically, offering a more potent and direct approach compared to topical applications.

AOD9604 is a synthetic peptide derived from the C-terminal fragment of human growth hormone (hGH), specifically amino acids 177-191, with an additional tyrosine residue at the N-terminus for stabilization. This 16-amino acid peptide was initially developed as a potential treatment for obesity, designed to mimic the lipolytic (fat-burning) properties of hGH without its growth-promoting or diabetogenic side effects. AOD9604 has shown promise in various applications, from weight management to tissue repair and regeneration, and has recently gained attention in the cosmetic industry for its potential to reduce cellulite and subcutaneous fat.

VIP (Vasoactive Intestinal Peptide) is a neuropeptide that reduces inflammation and regulates the immune system. It shows promise in treating neurodegenerative diseases and fibrosis-related conditions, offering potential benefits for cognitive function. Additionally, VIP may aid in managing mold toxicity by mitigating systemic and neuro-inflammatory responses.

MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA type-c) is a 16-amino acid peptide encoded by the mitochondrial 12S rRNA gene. Discovered in 2015, MOTS-c has emerged as a significant mitochondrial-derived peptide with diverse physiological functions. It plays crucial roles in regulating metabolism, stress responses, and aging-related processes. MOTS-c is unique in its ability to translocate to the nucleus under metabolic stress conditions, where it regulates nuclear gene expression to promote cellular adaptation and homeostasis.

Dihexa, also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide, is a synthetic peptide derived from angiotensin IV with powerful nootropic and neuroprotective properties. It is often described as a small molecule that can easily cross the blood-brain barrier, promoting synaptogenesis and neurogenesis. Dihexa has been studied for its potential to enhance cognitive function, memory, and learning capabilities, as well as for its role in repairing damaged neural connections. Its unique mechanism of action involves binding to hepatocyte growth factor (HGF), which plays a critical role in brain plasticity and repair.

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide naturally occurring in the thymus gland. It is derived from a larger protein called prothymosin alpha, encoded by the PTMA gene in humans. Tα1 has long been recognized for its ability to modify, enhance, and restore immune function. As an immunomodulatory peptide, it plays crucial roles in T cell differentiation, development, and maturation. Synthetic versions of Tα1, such as thymalfasin, have been developed and approved in over 35 countries for various clinical applications, particularly in treating viral infections, immunodeficiency disorders, and as an adjunct therapy in certain cancers.

Epitalon, also known as Epithalon or Epithalone, is a synthetic tetrapeptide derived from a naturally occurring peptide in the pineal gland called epithalamin. It was discovered in the 1980s by Russian scientist Professor Vladimir Khavinson and has since become a subject of significant interest in anti-aging and longevity research. Epitalon is composed of four amino acids (Ala-Glu-Asp-Gly) and is known for its potential to regulate gene expression, influence telomere length, and modulate various physiological processes associated with aging.

N-Acetyl Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment, specifically designed to enhance cognitive function and provide neuroprotection. This acetylated variant of Semax is engineered to improve stability and penetration into the brain, making it a promising candidate for cognitive enhancement and neuroprotective applications. The acetylation of the N-terminus increases the peptide's resistance to enzymatic degradation, enhancing its stability and bioavailability. This structural modification allows N-Acetyl Semax to effectively cross the blood-brain barrier and exert its effects on the central nervous system.

ARA-290 is a synthetic peptide derived from the tertiary structure of erythropoietin (EPO). It is specifically designed to activate the innate repair receptor (IRR), which mediates tissue protection and repair without the erythropoietic effects of EPO. ARA-290 is a small, 11-amino acid peptide with a molecular weight of 1257 daltons that mimics the spatial configuration of the B-helix of the EPO molecule. This peptide has shown promising results in reducing neuropathic pain, promoting tissue repair, and improving metabolic control in various preclinical and clinical studies.

Delta Sleep-Inducing Peptide (DSIP) is a naturally occurring neuropeptide first isolated from the cerebral venous blood of rabbits in 1977 by the Schoenenberger-Monnier group from Basel. Initially thought to be a sleep-promoting factor, DSIP is now recognized as a multifunctional regulatory peptide with a wide range of physiological activities. Despite extensive research, its precise biological role and mechanism of action remain unclear, leading some researchers to describe it as an "unresolved riddle" in neuroscience.

Nicotinamide Adenine Dinucleotide (NAD+) is a critical coenzyme found in all living cells that plays a central role in cellular metabolism and energy production. It functions as an electron carrier in redox reactions and serves as a substrate for various enzymes involved in cellular processes such as DNA repair, gene expression regulation, and cellular signaling. NAD+ levels tend to decline with age, and this decline has been associated with various age-related diseases and metabolic disorders. Consequently, NAD+ has emerged as a promising target for therapeutic interventions aimed at improving healthspan and potentially lifespan.